Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | GRK3 | P35626 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879862 | 1.00 | MAPT (0.43) | MAPTLMNAALDH1A1CSNK1DDGAT2 | |
| SCHEMBL5879822 | 0.90 | MAPT (0.51) | MAPTLMNAALDH1A1RXFP1CYP1A2 | |
| SCHEMBL5879818 | 0.90 | MAPT (0.51) | MAPTLMNAALDH1A1RXFP1CYP1A2 | |
| SCHEMBL5879917 | 0.90 | FFAR2 (0.41) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5879913 | 0.90 | FFAR2 (0.41) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5880215 | 0.89 | MAPT (0.46) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5880218 | 0.89 | MAPT (0.46) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5880014 | 0.88 | MAPT (0.45) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5880269 | 0.88 | MAPT (0.45) | MAPTLMNAALDH1A1CSNK1DFFAR2 | |
| SCHEMBL5880265 | 0.88 | MAPT (0.45) | MAPTLMNAALDH1A1CSNK1DFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |