(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL5880315

C(=Cc1ccccc1)c1ccccc1.C=CCN(CC=C)S(=O)(=O)N(CC=C)CC=C

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALOX12 P18054 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
RAB9A P51151 1/20 0.40
ESR1 P03372 1/20 0.40
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11031928 0.77 KDM4E (0.39) ALDH1A1MEN1KMT2ARAB9AGAA
SCHEMBL973944 0.77 KDM4E (0.39) ALDH1A1MEN1KMT2ARAB9AGAA
SCHEMBL4262910 0.73 ESR1 (0.53) ALDH1A1MEN1KMT2AALOX12NPSR1
SCHEMBL10886298 0.72 RELA (0.57) ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL6742362 0.71 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2HDAC3
SCHEMBL473073 0.71 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2HDAC3
SCHEMBL5180539 0.70 HSP90AA1 (0.49) MEN1KMT2ARAB9AESR1S1PR1
(Z)-1,2-Diphenylethene SCHEMBL28059396 0.70 MAOB (0.61) ALDH1A1MEN1KMT2ASMN1; SMN2HDAC3
SCHEMBL2106139 0.69 MEN1 (0.54) ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
(Z)-1,2-Diphenylethene SCHEMBL4657880 0.69 HDAC1 (0.62) ALDH1A1SMN1; SMN2HDAC3TNKSHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7016580-B1 Grating- and polymer-based optical attenuators and modulators TRANS PHOTONICS, L.L.C. (US) 2006-03-21 US claimed
US-6665479-B2 Polymeric devices including optical waveguide laser and optical amplifier SHAYDA TECHNOLOGIES, INC. 2003-12-16 US claimed
WO-2002071557-A2 POLYMERIC WAVEGUIDE LASER AND AMPLIFIER SHAYDA TECHNOLOGIES, INC. (US) 2002-09-12 WO claimed
US-20020009274-A1 Novel polymeric devices including optical waveguide laser and optical amplifier GOVERNMENT OF THE U.S. OF AMERICA 2002-01-24 US claimed
US-7016580-B1 Grating- and polymer-based optical attenuators and modulators TRANS PHOTONICS, L.L.C. (US) 2006-03-21 US disclosed
US-6665479-B2 Polymeric devices including optical waveguide laser and optical amplifier SHAYDA TECHNOLOGIES, INC. 2003-12-16 US disclosed
WO-2002071557-A2 POLYMERIC WAVEGUIDE LASER AND AMPLIFIER SHAYDA TECHNOLOGIES, INC. (US) 2002-09-12 WO disclosed
US-20020009274-A1 Novel polymeric devices including optical waveguide laser and optical amplifier GOVERNMENT OF THE U.S. OF AMERICA 2002-01-24 US disclosed