SCHEMBL473073

SCHEMBL473073

C=CCN(C=Cc1ccccc1)CC=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAOB P27338 2/20 0.41
TSHR P16473 1/20 0.41
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742362 1.00 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAOBTSHRHDAC3
SCHEMBL11128935 0.86 MAOB (0.52) ALDH1A1SMN1; SMN2MAOBTSHRHDAC3
SCHEMBL3631015 0.78 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAOBTSHRHDAC3
SCHEMBL11171879 0.74 NPC1 (0.48) MAOBRELAGRM5TRPA1
SCHEMBL136178 0.74 NPC1 (0.48) MAOBRELAGRM5TRPA1
SCHEMBL2106139 0.73 MEN1 (0.54) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL10886298 0.72 RELA (0.57) ALDH1A1SMN1; SMN2MAOBTSHRMEN1
SCHEMBL5823784 0.72 MAOB (0.52) MAOBCYP1A2MAPK1
SCHEMBL4267036 0.71 MAOB (0.41) ALDH1A1SMN1; SMN2MAOBHDAC3TNKS
SCHEMBL10626718 0.71 NPC1 (0.42) MAOBMEN1KMT2ARELAGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3401369-B1 PROCESS FOR MAKING AN ANTI-REFLECTIVE COATING COMPOSITION AND A POROUS COATING MADE THEREFROM COVESTRO NETHERLANDS BV (NL) 2023-07-19 EP claimed
EP-3807378-A1 METHOD FOR ASSESSING THE COMPATIBILITY OF PRODUCTION FLUID ADDITIVES Anpera Technologies Limited (GB) 2021-04-21 EP claimed
WO-2019243792-A1 METHOD FOR ASSESSING THE COMPATIBILITY OF PRODUCTION FLUID ADDITIVES LUX ASSURE LIMITED (GB) 2019-12-26 WO claimed
CN-104112722-B Semiconductor devices including the material for absorbing heat energy 英飞凌科技奥地利有限公司 2017-06-09 CN claimed
EP-2185127-B1 COSMETIC COMPOSITIONS CONTAINING A POLYMER BLEND ELC MAN LLC (US) 2016-04-06 EP claimed
US-9165847-B2 Semiconductor device including a material to absorb thermal energy INFINEON TECHNOLOGIES AUSTRIA AG (AT) 2015-10-20 US claimed
US-20140312394-A1 Semiconductor Device Including a Material to Absorb Thermal Energy INFINEON TECHNOLOGIES AUSTRIA AG (AT) 2014-10-23 US claimed
US-8562960-B2 Cosmetic composition containing a polymer blend ELC MANAGEMENT, LLC (US) 2013-10-22 US claimed
US-20120301416-A1 Cosmetic Composition Containing A Polymer Blend ELC MANAGEMENT LLC 2012-11-29 US claimed
EP-2242541-A1 GLOW AND SUNLESS TANNING COLOUR ENHANCEMENT BY CATIONIC COPOLYMERS Unilever PLC (GB) 2010-10-27 EP claimed
US-20090208442-A1 CATIONIC COPOLYMERS FORMULATED WITH PIGMENTED COSMETIC COMPOSITIONS EXHIBITING RADIANCE WITH SOFT FOCUS CONOPCO, INC., D/B/A UNILEVER (US) 2009-08-20 US claimed
US-20090208430-A1 GLOW AND SUNLESS TANNING COLOR ENHANCEMENT BY CATIONIC COPOLYMERS CONOPCO, INC., D/B/A UNILEVER (US) 2009-08-20 US claimed
US-20090035335-A1 Cosmetic Composition Containing a Polymer Blend ELC MANAGEMENT LLC 2009-02-05 US claimed
WO-2009018064-A2 COSMETIC COMPOSITIONS CONTAINING A POLYMER BLEND ELC MANAGEMENT LLC (US) 2009-02-05 WO claimed
US-20060051648-A1 Solid polymer electrolyte membrane, method for producing the same, and fuel cell including the solid poymer electrolyte membrane SAMSUNG SDI CO. LTD. (KR) 2006-03-09 US claimed
US-20050249684-A1 Taurate formulated pigmented cosmetic composition exhibiting radiance with soft focus UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-11-10 US claimed
WO-2005070384-A1 TAURATE FORMULATED PIGMENTED COSMETIC COMPOSITION EXHIBITIING RADIANCE WITH SOFT FOCUS UNILEVER PLC (GB) 2005-08-04 WO claimed
US-20020061319-A1 Film-forming cosmetic composition L'OREAL S.A. (FR) 2002-05-23 US claimed
US-6335005-B1 Aqueous cosmetic compounds BASF AKTIENGESELLSCHAFT (DE) 2002-01-01 US claimed
WO-1999002610-A1 UV CURABLE COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-01-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050249684-A1 Taurate formulated pigmented cosmetic composition exhibiting radiance with soft focus ZRANB2, CUTA, SLC39A3 ALDH1A1 4669/4885SMN1; SMN2 2565/4885MAOB 1941/4885
US-20020061319-A1 Film-forming cosmetic composition KRT18, F8, CUTA ALDH1A1 1642/4885SMN1; SMN2 3768/4885MAOB 1068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.