Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685460 | 0.86 | DPP4 (0.44) | SLC6A4HTTSLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL919270 | 0.81 | MAPT (0.43) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL8700819 | 0.81 | HTR2A (0.45) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL10469324 | 0.79 | GAA (0.45) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL15732451 | 0.77 | CYP1A2 (0.42) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL8123557 | 0.75 | PDE7A (0.43) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL8126361 | 0.74 | LMNA (0.47) | HTTMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7017882 | 0.72 | CYP1A2 (0.41) | HTR2ASLC6A4HTTSLC6A2SLC6A3 | |
| SCHEMBL315016 | 0.71 | — | — | |
| SCHEMBL9321769 | 0.71 | HTR2A (0.53) | HTR2ASLC6A4HTTSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989351-B2 | Metabolic inhibitors against brassinosteroids | RIKEN (JP) | 2006-01-24 | — | — | US | disclosed |
| US-20040259735-A1 | Metabolic inhibitors against brassinosteroids | RIKEN (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1304038-A1 | METABOLIC INHIBITORS AGAINST BRASSINOSTEROIDS | RIKEN (JP) | 2003-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259735-A1 | Metabolic inhibitors against brassinosteroids | DBI, HSD17B4, ABHD5 | HTR2A 4154/4885SLC6A4 3338/4885HTT 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.