Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880902 | 0.95 | SIGMAR1 (0.38) | SIGMAR1GRIN2BFUCA1GRIN1 | |
| SCHEMBL5881066 | 0.90 | GRIN2B (0.35) | SIGMAR1GRIN2BFUCA1L3MBTL1 | |
| SCHEMBL5881020 | 0.77 | TDP1 (0.33) | — | |
| SCHEMBL28856438 | 0.73 | MAOA (0.32) | SIGMAR1 | |
| SCHEMBL5881023 | 0.70 | — | — | |
| SCHEMBL5881085 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL28102667 | 0.66 | IDO1 (0.31) | — | |
| SCHEMBL28253806 | 0.65 | — | — | |
| SCHEMBL3976323 | 0.65 | — | — | |
| SCHEMBL4566706 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122570-B2 | Tetrahydrocarbazol derivatives as ligands for G-protein-coupled receptors (GPCR) | ZENTARIS AG (DE) | 2006-10-17 | — | — | US | disclosed |