Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111604 | 0.93 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL7117424 | 0.91 | MAPT (0.35) | MAOAMAOB | |
| SCHEMBL2063931 | 0.84 | — | — | |
| SCHEMBL1578618 | 0.79 | DUT (0.37) | — | |
| SCHEMBL7882674 | 0.76 | — | — | |
| SCHEMBL662237 | 0.76 | DUT (0.36) | MAOAMAOB | |
| SCHEMBL7052818 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL12598353 | 0.75 | — | — | |
| SCHEMBL23727498 | 0.74 | DUT (0.35) | — | |
| SCHEMBL5244051 | 0.74 | MAOA (0.30) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800525-B1 | PROCESS FOR PREPARING TRIMETHYLSILYLOXY FUNCTIONALIZED ALKYLLITHIUM COMPOUNDS | FMC CORP (US) | 2003-04-09 | — | — | EP | claimed |
| US-6989450-B2 | Synthesis of epothilones and related analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 2006-01-24 | — | — | US | disclosed |
| EP-1414384-A4 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | UNIV MISSISSIPPI (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1414384-A2 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | The University of Mississippi (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20020091269-A1 | Synthesis of epothilones and related analogs | TAPESTRY PHARMACEUTICALS, INC. | 2002-07-11 | — | — | US | disclosed |
| WO-2002030356-A2 | SYNTHESIS OF EPOTHILONES AND RELATES ANALOGS | THE UNIVERSITY OF MISSISSIPI (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-1999064048-A9 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | ADVANCED MEDICINE INC (US) | 2000-07-20 | — | — | WO | disclosed |
| EP-1003541-A1 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | Advanced Medicine, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999064048-A1 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998040341-A1 | PROCESS FOR PREPARATION OF CYCLOPENTENONES IN SUPERCRITICAL FLUIDS | HANIL SYNTHETIC FIBER CO., LTD. (KR) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091269-A1 | Synthesis of epothilones and related analogs | DHPS, SQLE, FDFT1 | MAOA 1284/4885MAOB 1048/4885CA12 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.