SCHEMBL8979351

SCHEMBL8979351

COC(=O)c1cc(C)cc(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.56
ATM Q13315 1/20 0.52
ALDH1A1 P00352 5/20 0.51
MAPT P10636 4/20 0.51
MEN1 O00255 1/20 0.51
HPGD P15428 1/20 0.51
XBP1 P17861 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 3/20 0.48
XDH P47989 2/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570165 1.00 CNR2 (0.56) CNR2ATMALDH1A1MAPTMEN1
SCHEMBL67540 0.87 ALDH1A1 (0.62) CNR2ALDH1A1MAPTMEN1HPGD
SCHEMBL588343 0.87 ALDH1A1 (0.62) CNR2ALDH1A1MAPTMEN1HPGD
SCHEMBL70232 0.85 ATM (0.61) CNR2ATMALDH1A1MAPTCA12
Methyl 3,5-Dimethylbenzoate SCHEMBL334346 0.85 CNR2 (0.66) CNR2ATMALDH1A1MAPTMEN1
SCHEMBL27866773 0.82 HTR3E (0.40) CNR2ALDH1A1MAPTMEN1HPGD
SCHEMBL15615318 0.81 CA12 (0.56) CNR2MEN1KMT2ACA12CA1
SCHEMBL4734613 0.80 ALDH1A1 (0.56) CNR2ALDH1A1MAPTMEN1HPGD
SCHEMBL5185978 0.80 CA12 (0.73) CNR2ALDH1A1MAPTMEN1HPGD
SCHEMBL16961231 0.80 ALDH1A1 (0.56) CNR2ALDH1A1MAPTMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025131957-A1 DIAZINONE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2025-06-26 WO disclosed
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD SPRINGWORKS THERAPEUTICS, INC. (US) 2024-07-09 US disclosed
CN-115551839-B Heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-04 CN disclosed
US-20230346764-A1 Methods and Compositions for Treating Pruritus, Xerosis, and Associated Disease Using CCR3-Inhibitors ALKAHEST, INC. 2023-11-02 US disclosed
EP-3875151-B1 ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO [4.3.1] DECANE DERIVATES FOR TREATMENT OF PSYCHIATRIC DISORDERS UNIV DARMSTADT TECH (DE) 2023-09-20 EP disclosed
CN-116730977-A Novel aryl heterocyclic compound, and preparation method and application thereof 华东理工大学 2023-09-12 CN disclosed
CN-116724015-A Process for preparing insecticidal anthranilamides UPL有限公司 2023-09-08 CN disclosed
US-20230278982-A1 2-Pyrazole Anilines and Related Analogs for Inhibiting YAP/TAZ-TEAD KU LEUVEN R&D (BE) 2023-09-07 US disclosed
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
US-20120149661-A1 TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS NOVARTIS AG (CH) 2012-06-14 US disclosed
US-20110190301-A1 SUBSTITUTED CYCLOPENTANES OR CYCLOPENTANONES AS THERAPEUTIC AGENTS ALLERGAN, INC. (US) 2011-08-04 US disclosed
US-7763597-B2 Salts ASTRAZENECA AB (SE) 2010-07-27 US disclosed
WO-2009034029-A2 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-03-19 WO disclosed
US-20080269176-A1 New Salts ASTRAZENECA AB (SE) 2008-10-30 US disclosed
US-7329769-B2 Catalytic boronate ester synthesis from boron reagents and hydrocarbons BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-02-12 US disclosed
US-7273858-B2 Sulfonic acid salts of 2-(p-(alkoxyamidino)benzylaminocarbonyl)azetidin-1-yl 3-chloro-5-(fluorinated alkoxy)-alpha-hydroxybenzyl ketone; competitive inhibitors of trypsin-like proteases, such as thrombin; anticoagulants ASTRAZENECA AB (SE) 2007-09-25 US disclosed
EP-0604019-B1 N-Acetonylbenzamides and their use as fungicides ROHM & HAAS (US) 1996-05-08 EP disclosed
EP-0604019-A1 N-Acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1994-06-29 EP disclosed
US-5254584-A Controlling phytopathogens ROHM AND HAAS COMPANY (US) 1993-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269176-A1 New Salts PRSS1, PRSS2, CTRL CNR2 3541/4885ATM 3177/4885ALDH1A1 898/4885
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES PRXL2A, GLRX3, CYP4F3 CNR2 1146/4885ATM 3528/4885ALDH1A1 4213/4885
US-20120149661-A1 TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS MDM4, MDM2, TP53 CNR2 3405/4885ATM 660/4885ALDH1A1 4361/4885
US-20230278982-A1 2-Pyrazole Anilines and Related Analogs for Inhibiting YAP/TAZ-TEAD YAP1, TEAD3, TEAD2 CNR2 4202/4885ATM 400/4885ALDH1A1 2212/4885
US-20230346764-A1 Methods and Compositions for Treating Pruritus, Xerosis, and Associated Disease Using CCR3-Inhibitors CCR3, CCR1, CCR4 CNR2 553/4885ATM 3275/4885ALDH1A1 4741/4885
US-20110190301-A1 SUBSTITUTED CYCLOPENTANES OR CYCLOPENTANONES AS THERAPEUTIC AGENTS PTGIS, PTGIR, PDE3A CNR2 329/4885ATM 3586/4885ALDH1A1 775/4885
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD YAP1, TEAD3, TEAD2 CNR2 4202/4885ATM 400/4885ALDH1A1 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.