Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884127 | 0.90 | KCNH2 (0.41) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884658 | 0.89 | DRD2 (0.40) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884836 | 0.88 | HTR4 (0.46) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884577 | 0.88 | SLC6A2 (0.43) | DRD3DRD2LTA4HSLC6A2SLC6A4 | |
| SCHEMBL5884891 | 0.87 | DRD2 (0.39) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884502 | 0.86 | DRD2 (0.41) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884362 | 0.84 | NR1I2 (0.38) | MAPTHPGDGAA | |
| SCHEMBL5884356 | 0.83 | HRH3 (0.38) | DRD3DRD2DRD1DRD5KDM4E | |
| SCHEMBL5885004 | 0.78 | HTR4 (0.42) | DRD3DRD2DRD1DRD5LTA4H | |
| SCHEMBL5884418 | 0.78 | SLC6A2 (0.41) | DRD2LTA4HSLC6A2SLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |