Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885004 | 0.90 | HTR4 (0.42) | HTR4AXLALDH1A1LMNALTA4H | |
| SCHEMBL5884648 | 0.89 | HTR4 (0.42) | HTR4AXLALDH1A1LMNALTA4H | |
| SCHEMBL5883875 | 0.88 | DRD3 (0.42) | LMNALTA4HDRD2DRD1DRD5 | |
| SCHEMBL5883939 | 0.88 | SMN1; SMN2 (0.45) | HTR4AXLALDH1A1LMNALTA4H | |
| SCHEMBL5883893 | 0.86 | AXL (0.41) | HTR4AXLALDH1A1LMNALTA4H | |
| SCHEMBL5884502 | 0.85 | DRD2 (0.41) | LTA4HPTGS2DRD2DRD1DRD5 | |
| SCHEMBL5884268 | 0.84 | MEN1 (0.43) | AXLALDH1A1LMNABPTFPTGS2 | |
| SCHEMBL5884759 | 0.83 | MEN1 (0.43) | ALDH1A1LMNABPTFPTGS2CYP1A2 | |
| SCHEMBL9212665 | 0.79 | DRD2 (0.52) | HTR4ALDH1A1LMNADRD2DRD1 | |
| SCHEMBL5883978 | 0.79 | KMT2A (0.39) | AXLBPTFPTGS2CYP1A2PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |