SCHEMBL588391

SCHEMBL588391

O=C(O)c1cc(Br)cc(Br)c1Br

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.65
AKR1C2 P52895 2/20 0.65
AKR1C1 Q04828 2/20 0.65
AKR1C4 P17516 1/20 0.65
HSD17B10 Q99714 1/20 0.57
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
GPR35 Q9HC97 3/20 0.46
LCK P06239 2/20 0.41
FYN P06241 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPE1 P61604 1/20 0.41
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTPN1 P18031 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437956 0.87 AKR1C3 (0.60) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL330545 0.79 AKR1C3 (1.00) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL7682107 0.79 AKR1C3 (0.47) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL31424007 0.79 AKR1C3 (0.63) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL6431790 0.79 TTR (0.58) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL29387062 0.79 AKR1C3 (1.00) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL49516 0.78 EIF2AK2 (0.45) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL23699506 0.77 AKR1C3 (0.61) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL9398447 0.77 AKR1C3 (0.96) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL2226763 0.77 AKR1C3 (0.61) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN claimed
EP-2005972-A1 Contrast agents for medical devices Cordis Corporation (US) 2008-12-24 EP claimed
US-20070123622-A1 ETHER-ESTER PLASTICIZERS FERRO CORPORATION (US) 2007-05-31 US claimed
EP-1456322-A4 GLYCERIN TRIESTER PLASTICIZER FERRO CORP (US) 2005-03-16 EP claimed
EP-1456322-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2004-09-15 EP claimed
WO-2003054106-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2003-07-03 WO claimed
US-20030116750-A1 Glycerin triester plasticizer POLYMER ADDITIVES, INC. 2003-06-26 US claimed
WO-2025072511-A1 TAILORING NON-EQUILIBRIUM PATHWAYS FOR THE SELECTIVE FORMATION OF INTERMEDIATE COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO disclosed
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN disclosed
US-10816899-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-27 US disclosed
US-8115029-B2 Oxidizing a substrate using a catalyst of a complex of cobalt and N-hydroxysuccinimide, N-hydroxyphthalimide, or N-hydroxymaleimide; alkanes, alkenes, cycloalkanes, cycloalkenes, aromatics, aryl aldehydes, aryl carboxylic acids, benzyl alcohols UNIVERSITY OF KANSAS (US) 2012-02-14 US disclosed
US-7498372-B2 Phthalate-free; such as 3-benzyloxy-1,2-propyl dibenzoate; for use with vinyl polymers, rubbers, polyurethanes, and acrylics FERRO CORPORATION (US) 2009-03-03 US disclosed
US-20080139841-A1 Cobalt-Catalyzed Oxidations in Volumetrically Expanded Liquids by Compressed Gases UNIVERSITY OF KANSAS (US) 2008-06-12 US disclosed
EP-1362840-A1 Process for the preparation of aromatic and heteroaromatic carboxylic acids via catalytic ozonolysis DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2003-11-19 EP disclosed
WO-2003054106-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2003-07-03 WO disclosed
US-20030120104-A1 Glycerin triester plasticizer FERRO CORPORATION (US) 2003-06-26 US disclosed
US-20030116750-A1 Glycerin triester plasticizer POLYMER ADDITIVES, INC. 2003-06-26 US disclosed
CN-1369474-A 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process WANG JINGHENG (CN) 2002-09-18 CN disclosed
CN-1369474-A 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process WANG JINGHENG (CN) 2002-09-18 CN disclosed
CN-1369474-A 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process WANG JINGHENG (CN) 2002-09-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139841-A1 Cobalt-Catalyzed Oxidations in Volumetrically Expanded Liquids by Compressed Gases HAO2, HMOX2, HAAO AKR1C3 817/4885AKR1C2 778/4885AKR1C1 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.