Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RXRA | P19793 | 5/20 | 0.44 |
| ▸ | RARA | P10276 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883927 | 1.00 | CYP1A2 (0.51) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL7898750 | 0.81 | CYP1A2 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL7898751 | 0.81 | CYP1A2 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL11070445 | 0.80 | CYP1A2 (0.56) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL11070449 | 0.80 | CYP1A2 (0.56) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL8458864 | 0.78 | ALDH1A1 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL8950189 | 0.78 | ALDH1A1 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL8776535 | 0.78 | ALDH1A1 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL19652488 | 0.78 | ALDH1A1 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL8462052 | 0.78 | ALDH1A1 (0.57) | CYP1A2ALDH1A1PTGS1LMNADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188592-B2 | 2-pyrones | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20170014325-A1 | 2-PYRONES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9499508-B2 | 2-pyrones | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20130261175-A1 | 2-PYRONES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-7132558-B1 | Silicone vitamin esters | SURFATECH CORPORATION (US) | 2006-11-07 | — | — | US | disclosed |
| US-5210133-A | For hydroxyl functional active components, cosmetics, hair conditioners, effective water solubility or oil solubility, lanolin, cholesterol, vitamins A, D, E | SILTECH INC. (US) | 1993-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014325-A1 | 2-PYRONES | PYCR1, CYP17A1, CYP11B2 | CYP1A2 31/4885ALDH1A1 658/4885PTGS1 403/4885 |
| US-20130261175-A1 | 2-PYRONES | PYCR1, CYP17A1, CYP11B2 | CYP1A2 31/4885ALDH1A1 658/4885PTGS1 403/4885 |
| US-10188592-B2 | 2-pyrones | PYCR1, CYP17A1, CYP11B2 | CYP1A2 31/4885ALDH1A1 658/4885PTGS1 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.