Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968195 | 0.72 | — | — | |
| SCHEMBL8178618 | 0.71 | L3MBTL1 (0.55) | L3MBTL1PTK2 | |
| SCHEMBL1007992 | 0.70 | — | — | |
| SCHEMBL29036427 | 0.67 | KDR (0.36) | — | |
| SCHEMBL15360097 | 0.67 | — | — | |
| SCHEMBL13485374 | 0.67 | — | — | |
| SCHEMBL588407 | 0.67 | MAPK1 (0.37) | MAPK1L3MBTL1PTK2EDNRAHDAC3 | |
| Hydrochloric Acid SCHEMBL28846931 | 0.65 | GRM5 (0.42) | MAPK1L3MBTL1PTK2EDNRA | |
| Hydrochloric Acid SCHEMBL28846918 | 0.65 | GRM5 (0.42) | MAPK1L3MBTL1PTK2EDNRA | |
| SCHEMBL11470783 | 0.64 | PTK2 (0.58) | L3MBTL1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975149-B1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-7700808-B2 | 1-3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1975149-A1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | HCN1, CNPY2, CLIC1 | MAPK1 159/4885L3MBTL1 187/4885PTK2 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.