SCHEMBL5884129

SCHEMBL5884129

CCCCCC[N+](C)(CC#N)CCCCCC.O=S(=O)(O)c1ccccc1

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 known ✓ P14416 1/20 0.37
HTR2A known ✓ P28223 1/20 0.37
HRH1 known ✓ P35367 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
DNM1 Q05193 2/20 0.40
MAPK1 P28482 2/20 0.39
TP53 P04637 1/20 0.39
S1PR3 Q99500 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
EPHX2 P34913 1/20 0.37
ADRB2 P07550 3/20 0.37
ADRB1 P08588 3/20 0.37
MLNR O43193 1/20 0.37
NR1I2 O75469 1/20 0.37
ESR1 P03372 1/20 0.37
NR3C1 P04150 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330814 0.89 SMN1; SMN2 (0.52) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL330794 0.89 SMN1; SMN2 (0.52) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL330563 0.89 SMN1; SMN2 (0.52) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL331266 0.89 SMN1; SMN2 (0.52) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL4539901 0.88 KCNH2 (0.42) SMN1; SMN2TSHRHTTS1PR3TDP1
SCHEMBL5080911 0.86 KCNH2 (0.42) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL8444684 0.86 SMN1; SMN2 (0.40) SMN1; SMN2TSHRHTTMEN1KMT2A
Cetrimonium SCHEMBL331885 0.84 SMN1; SMN2 (0.53) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL331100 0.84 SMN1; SMN2 (0.53) SMN1; SMN2TSHRHTTMEN1KMT2A
SCHEMBL331151 0.84 SMN1; SMN2 (0.53) SMN1; SMN2TSHRHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015185-B2 Ammonium nitriles and the use thereof as hydrophobic bleaching activators CLARIANT GMBH (DE) 2006-03-21 US disclosed
US-20040266644-A1 Ammonium nitriles and the use thereof as hydrophobic bleaching activators CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2004-12-30 US disclosed