Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883844 | 0.91 | MEN1 (0.38) | HTTATMMEN1KMT2AALDH1A1 | |
| SCHEMBL5884261 | 0.87 | PPARG (0.37) | MEN1HRH3PPARGPPARDHPGD | |
| SCHEMBL5884324 | 0.79 | PPARG (0.46) | KMT2AALDH1A1PPARGPPARDPPARA | |
| SCHEMBL5884212 | 0.78 | RXFP1 (0.37) | MEN1KMT2AALDH1A1HRH3PPARG | |
| SCHEMBL5884362 | 0.77 | NR1I2 (0.38) | HPGD | |
| SCHEMBL5884475 | 0.76 | TDP1 (0.41) | HTTALDH1A1 | |
| SCHEMBL5884268 | 0.76 | MEN1 (0.43) | HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5884348 | 0.76 | MAPT (0.37) | HRH3 | |
| SCHEMBL5884624 | 0.75 | GPR119 (0.44) | — | |
| SCHEMBL5884262 | 0.74 | GPR119 (0.37) | KMT2AALDH1A1HRH3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |