Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884323 | 1.00 | CDK4 (0.42) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5950193 | 0.85 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL629142 | 0.85 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL1169909 | 0.83 | TDP1 (0.41) | ELANELMNAALDH1A1TDP1MEN1 | |
| SCHEMBL3359315 | 0.80 | ALDH1A1 (0.37) | LMNAALDH1A1ATG4B | |
| SCHEMBL2491664 | 0.80 | TDP1 (0.37) | ELANELMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL6090752 | 0.79 | ATG4B (0.42) | TRPA1ATG4BBCHEACHE | |
| SCHEMBL6090762 | 0.79 | ATG4B (0.42) | TRPA1ATG4BBCHEACHE | |
| SCHEMBL3362751 | 0.79 | TDP1 (0.40) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9104204 | 0.78 | ALDH1A1 (0.41) | LMNAALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078542-B2 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON (US) | 2006-07-18 | — | — | US | disclosed |
| US-7014796-B2 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON (US) | 2006-03-21 | — | — | US | disclosed |
| US-20050023507-A1 | pi-electron donor group bonded to a pi-electron conjugated bridge group bonded to a mono- or dicyanodihydrofuran acceptor; large hyperpolarizability, dipole moment, and electrooptic coefficients; electrooptics | UNIVERSITY OF WASHINGTON (US) | 2005-02-03 | — | — | US | disclosed |
| WO-2004065384-A1 | NONLINEAR OPTICAL COMPOUNDS AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF WASHINGTON (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20040135130-A1 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050023507-A1 | pi-electron donor group bonded to a pi-electron conjugated bridge group bonded to a mono- or dicyanodihydrofuran acceptor; large hyperpolarizability, dipole moment, and electrooptic coefficients; electrooptics | PCNA, ETFA, POF1B | CDK4 117/4885CCND1 232/4885CCNB2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.