Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884689 | 0.95 | KCNH2 (0.39) | KCNH2L3MBTL1NR1I2MAPTGPR119 | |
| SCHEMBL5884333 | 0.95 | KCNH2 (0.39) | KCNH2L3MBTL1NR1I2MAPTGPR119 | |
| SCHEMBL5884514 | 0.92 | NR1I2 (0.35) | KCNH2L3MBTL1NR1I2MAPTGPR119 | |
| SCHEMBL5884554 | 0.90 | MEN1 (0.39) | KCNH2L3MBTL1MAPTKMT2AHRH3 | |
| SCHEMBL5884356 | 0.90 | HRH3 (0.38) | L3MBTL1NR1I2MAPTGPR119HRH3 | |
| SCHEMBL14191686 | 0.89 | NR1I2 (0.38) | KCNH2L3MBTL1NR1I2MAPTGPR119 | |
| SCHEMBL5883890 | 0.89 | DGAT1 (0.35) | KCNH2OPRK1 | |
| SCHEMBL5884287 | 0.88 | L3MBTL1 (0.37) | KCNH2L3MBTL1NR1I2MAPTGPR119 | |
| SCHEMBL5884955 | 0.87 | KCNH2 (0.40) | KCNH2L3MBTL1MAPTKMT2AHRH3 | |
| SCHEMBL5884831 | 0.87 | TEAD1 (0.36) | KCNH2L3MBTL1NR1I2MAPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |