Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 3/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884592 | 0.95 | NPC1 (0.35) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884901 | 0.92 | GLS (0.33) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884910 | 0.91 | SMN1; SMN2 (0.37) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884729 | 0.91 | NPC1 (0.37) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5883881 | 0.91 | L3MBTL1 (0.34) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884353 | 0.89 | KCNH2 (0.39) | OPRK1KCNH2 | |
| SCHEMBL5884090 | 0.88 | NPY1R (0.44) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884713 | 0.88 | TEAD1 (0.36) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884586 | 0.86 | SMN1; SMN2 (0.37) | DGAT1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884326 | 0.86 | NPC1 (0.38) | DGAT1NPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |