Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | IL1B | P01584 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731340 | 0.93 | MAPT (0.48) | MAPTALDH1A1GAAIL1BTNF | |
| SCHEMBL1852259 | 0.85 | IL1B (0.53) | MAPTALDH1A1GAAIL1BTNF | |
| SCHEMBL3641438 | 0.79 | MAPT (0.48) | MAPTALDH1A1GAAHTR1AHTR1D | |
| SCHEMBL6861106 | 0.79 | MAPT (0.52) | MAPTALDH1A1GAAHTR1AHTR1D | |
| SCHEMBL18990020 | 0.76 | MAPT (0.46) | MAPTALDH1A1GAAIL1BTNF | |
| SCHEMBL6702206 | 0.74 | MAPT (0.55) | MAPTALDH1A1GAAIL1BTNF | |
| SCHEMBL5756006 | 0.72 | IL1B (0.53) | ALDH1A1GAAIL1BTNFNLRP3 | |
| SCHEMBL5676891 | 0.72 | MAPT (0.49) | MAPTALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5884495 | 0.71 | ALDH1A1 (0.43) | MAPTALDH1A1GAAHTR1AHTR1D | |
| SCHEMBL11726472 | 0.71 | MAPT (0.44) | MAPTALDH1A1GAAIL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | disclosed |