Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492587 | 0.80 | LMNA (0.45) | CYP1A2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4118891 | 0.75 | HRH3 (0.48) | ALDH1A1HRH3 | |
| SCHEMBL4128207 | 0.72 | HRH3 (0.50) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1300352 | 0.69 | NFE2L2 (0.61) | ALDH1A1HRH3 | |
| SCHEMBL8509290 | 0.68 | KDM4E (0.46) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8509285 | 0.68 | KDM4E (0.46) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7493508 | 0.68 | TEAD1 (0.39) | ALDH1A1 | |
| SCHEMBL7486949 | 0.68 | GPR119 (0.40) | ALDH1A1 | |
| SCHEMBL1299967 | 0.67 | NFE2L2 (0.64) | ALDH1A1HRH3 | |
| SCHEMBL8508526 | 0.67 | PDE10A (0.47) | AXLCHRNB1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | disclosed |