Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884657 | 0.92 | OPRK1 (0.36) | OPRK1ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL5884125 | 0.85 | HPGD (0.37) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884132 | 0.84 | LMNA (0.39) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884102 | 0.82 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884301 | 0.82 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5884402 | 0.82 | OPRK1 (0.33) | OPRK1PPARGPPARDPPARA | |
| SCHEMBL5883827 | 0.81 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884253 | 0.81 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884632 | 0.79 | HPGD (0.41) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884586 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |