Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884125 | 0.87 | HPGD (0.37) | HPGDLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5884301 | 0.86 | SMN1; SMN2 (0.40) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5884253 | 0.82 | KMT2A (0.40) | MAPTLMNASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL5883827 | 0.82 | KMT2A (0.40) | MAPTLMNASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL5884586 | 0.81 | SMN1; SMN2 (0.37) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5884620 | 0.80 | HPGD (0.35) | HPGDLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5884576 | 0.79 | MEN1 (0.37) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5884485 | 0.79 | HPGD (0.38) | HPGDMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5884625 | 0.78 | MEN1 (0.39) | LMNASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL5883897 | 0.78 | LMNA (0.41) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |