Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.36 |
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884232 | 0.92 | FFAR1 (0.38) | FFAR1TLR4TLR2DGAT1DRD2 | |
| SCHEMBL5884909 | 0.92 | GAA (0.31) | FFAR1 | |
| SCHEMBL5884929 | 0.90 | DRD4 (0.33) | DRD2DRD4TTRRBP4BTK | |
| SCHEMBL5884768 | 0.89 | FFAR1 (0.39) | FFAR1TLR4TLR2DGAT1DRD2 | |
| SCHEMBL5884841 | 0.88 | CHRNB2 (0.34) | TLR4TLR2DRD2DRD4BTK | |
| SCHEMBL5884946 | 0.83 | MEN1 (0.33) | FFAR1TLR4TLR2DGAT1DRD2 | |
| SCHEMBL5884636 | 0.82 | DRD4 (0.34) | FFAR1DRD2DRD4TTRRBP4 | |
| SCHEMBL5884436 | 0.82 | FFAR1 (0.33) | FFAR1DRD2MAP4K4 | |
| SCHEMBL5884551 | 0.82 | HRH3 (0.33) | — | |
| SCHEMBL5884173 | 0.80 | KMT2A (0.43) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |