Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884713 | 0.96 | TEAD1 (0.36) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5883890 | 0.92 | DGAT1 (0.35) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884627 | 0.91 | L3MBTL1 (0.33) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884872 | 0.91 | SMN1; SMN2 (0.34) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884514 | 0.89 | NR1I2 (0.35) | MAOBMAOATEAD1TEAD3 | |
| SCHEMBL5884729 | 0.88 | NPC1 (0.37) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884914 | 0.88 | NPY1R (0.38) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884592 | 0.88 | NPC1 (0.35) | GLSNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL5884089 | 0.86 | SLC6A2 (0.40) | NPC1POLBRAB9ASMN1; SMN2MAOB | |
| SCHEMBL5884831 | 0.85 | TEAD1 (0.36) | NPC1RAB9ATEAD1TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |