Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.46 |
| ▸ | HTR3B | O95264 | 5/20 | 0.46 |
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22477603 | 0.87 | TP53 (0.40) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL5885352 | 0.87 | TP53 (0.40) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL5885691 | 0.86 | TP53 (0.39) | USP2ALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL5884801 | 0.85 | ADRB1 (0.38) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5885435 | 0.83 | ADRB1 (0.37) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5885514 | 0.78 | NAMPT (0.40) | HTR6USP2DRD2 | |
| SCHEMBL5884843 | 0.78 | RORC (0.37) | — | |
| SCHEMBL5885250 | 0.76 | RORC (0.39) | ALDH1A1MAPT | |
| SCHEMBL5885436 | 0.76 | PTPN1 (0.40) | SIGMAR1HTR6ALDH1A1DRD3MAPT | |
| SCHEMBL5884862 | 0.73 | MAPT (0.42) | USP2ALDH1A1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | claimed |
| CN-1245150-C | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2006-03-15 | — | — | CN | claimed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | claimed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | claimed |
| CN-1410047-A | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2003-04-16 | — | — | CN | claimed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-06-01 | — | — | US | disclosed |
| CN-1245150-C | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2006-03-15 | — | — | CN | disclosed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | disclosed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| CN-1410047-A | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2003-04-16 | — | — | CN | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | ADRB1 3120/4885HTR3E 2552/4885HTR3B 2310/4885 |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | ADRB1 3395/4885HTR3E 2230/4885HTR3B 1860/4885 |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | ADRB1 3395/4885HTR3E 2230/4885HTR3B 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.