SCHEMBL5886320

SCHEMBL5886320

CCCC1CCC(CCC2CCC(c3cccc([N+](=O)[O-])c3F)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
CYP2C9 P11712 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 5/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
OPRL1 P41146 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 3/20 0.33
CACNA1C Q13936 1/20 0.33
THRB P10828 1/20 0.33
ACHE P22303 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886318 1.00 ALDH1A1 (0.36) ALDH1A1CYP2C9KDM4EMAPTLMNA
SCHEMBL5886424 0.89 PDE4B (0.36) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL5886428 0.89 PDE4B (0.36) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL28522110 0.85 TDP1 (0.44) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL7060573 0.80 CYP2C9 (0.43) ALDH1A1CYP2C9MAPTLMNAMEN1
SCHEMBL5886415 0.80 CYP2C9 (0.43) ALDH1A1CYP2C9MAPTLMNAMEN1
SCHEMBL7566938 0.79 OPRL1 (0.44) ALDH1A1CYP2C9MAPTLMNAMEN1
SCHEMBL7566933 0.79 OPRL1 (0.44) ALDH1A1CYP2C9MAPTLMNAMEN1
SCHEMBL716244 0.78 OPRL1 (0.45) ALDH1A1CYP2C9MAPTLMNAMEN1
SCHEMBL28483699 0.78 OPRL1 (0.45) ALDH1A1CYP2C9MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-7112355-B2 Active matrix type liquid crystal display apparatus HITACHI LTD. (JP) 2006-09-26 US disclosed
US-20050084623-A1 Active matrix type liquid crystal display apparatus IPS ALPHA SUPPORT CO., LTD. (JP) 2005-04-21 US disclosed
US-6849309-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2005-02-01 US disclosed
US-6830787-B1 Active matrix liquid crystal display apparatus HITACHI, LTD. (JP) 2004-12-14 US disclosed
US-20030201422-A1 Active matrix type liquid crystal display apparatus HITACHI DISPLAYS, LTD. (JP) 2003-10-30 US disclosed
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP disclosed
US-20020039162-A1 ACTIVE MATRIX TYPE LIQUID CRYSTAL DISPLAY APPARATUS OHE MASAHITO (JP) 2002-04-04 US disclosed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP disclosed
US-6011606-A Parallel field active matrix type liquid crystal display using liquid crystal having particular electrical properties HITACHI, LTD. (JP) 2000-01-04 US disclosed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP disclosed