SCHEMBL5886428

SCHEMBL5886428

CCCCCCCC1CCC(c2cccc([N+](=O)[O-])c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.36
PDE4D Q08499 1/20 0.36
MAPT P10636 2/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PLK1 P53350 1/20 0.33
PLK3 Q9H4B4 1/20 0.33
HPGD P15428 1/20 0.33
CES2 O00748 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
OPRL1 P41146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886424 1.00 PDE4B (0.36) PDE4BPDE4DMAPTGAAMEN1
SCHEMBL5886318 0.89 ALDH1A1 (0.36) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL5886320 0.89 ALDH1A1 (0.36) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL28522110 0.82 TDP1 (0.44) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL7567383 0.81 OPRL1 (0.41) MAPTGAAMEN1KMT2AHPGD
SCHEMBL7567390 0.81 OPRL1 (0.41) MAPTGAAMEN1KMT2AHPGD
SCHEMBL7728070 0.79 OPRL1 (0.42) MAPTGAAMEN1KMT2AHPGD
SCHEMBL7728060 0.79 OPRL1 (0.42) MAPTGAAMEN1KMT2AHPGD
SCHEMBL7728065 0.79 OPRL1 (0.42) MAPTGAAMEN1KMT2AHPGD
SCHEMBL731290 0.79 OPRL1 (0.42) MAPTGAAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-7112355-B2 Active matrix type liquid crystal display apparatus HITACHI LTD. (JP) 2006-09-26 US disclosed
US-20050084623-A1 Active matrix type liquid crystal display apparatus IPS ALPHA SUPPORT CO., LTD. (JP) 2005-04-21 US disclosed
US-6849309-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2005-02-01 US disclosed
US-6830787-B1 Active matrix liquid crystal display apparatus HITACHI, LTD. (JP) 2004-12-14 US disclosed
US-20030201422-A1 Active matrix type liquid crystal display apparatus HITACHI DISPLAYS, LTD. (JP) 2003-10-30 US disclosed
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP disclosed
US-20020039162-A1 ACTIVE MATRIX TYPE LIQUID CRYSTAL DISPLAY APPARATUS OHE MASAHITO (JP) 2002-04-04 US disclosed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP disclosed
US-6011606-A Parallel field active matrix type liquid crystal display using liquid crystal having particular electrical properties HITACHI, LTD. (JP) 2000-01-04 US disclosed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP disclosed