Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7893161 | 0.96 | TDP1 (0.36) | HTR2AHRH1TDP1 | |
| SCHEMBL1067179 | 0.83 | — | — | |
| SCHEMBL9617235 | 0.83 | — | — | |
| SCHEMBL10762385 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL27282115 | 0.81 | — | — | |
| SCHEMBL2932820 | 0.77 | — | — | |
| SCHEMBL135840 | 0.74 | — | — | |
| SCHEMBL8060724 | 0.74 | — | — | |
| SCHEMBL27669385 | 0.74 | ALDH1A1 (0.33) | HTR2AHRH1TDP1 | |
| Hydrochloric Acid SCHEMBL377772 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406837-B1 | Cationic polysaccharides and reagents for their preparation | NAT STARCH CHEM INVEST (US) | 1995-10-18 | — | — | EP | claimed |
| US-5227481-A | Cationic polysaccharides and reagents for their preparation | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-07-13 | — | — | US | claimed |
| EP-0406837-A2 | Cationic polysaccharides and reagents for their preparation | National Starch and Chemical Investment Holding Corporation (US) | 1991-01-09 | — | — | EP | claimed |
| US-7132419-B2 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2006-11-07 | — | — | US | disclosed |
| US-20050143383-A1 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2005-06-30 | — | — | US | disclosed |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | XENOVA LIMITED (GB) | 2003-07-24 | — | — | US | disclosed |
| EP-1240148-A1 | BENZO[A]PHENAZIN-11-CARBOXAMIDE DERIVATIVES AND THEIR USE AS JOINT INHIBITORS OF TOPOMERASE I AND II | Xenova Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046157-A1 | BENZO[A]PHENAZIN-11-CARBOXAMIDE DERIVATIVES AND THEIR USE AS JOINT INHIBITORS OF TOPOMERASE I AND II | XENOVA LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |
| US-6193843-B1 | PREPARED BY REACTING A POLYSACCHARIDE WITH A POLYCATIONIC REAGENT HAVING ONE POLYSACCHARIDE REACTIVE GROUP AND AT LEAST TWO CATIONIC GROUPS; SUITABLE REAGENTS INCLUDE POLYCATIONIC ALKYL, ARYL, ALKARYL, CYCLOALIPHATIC, OR HETEROCYCLIC AMINES | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-02-27 | — | — | US | disclosed |
| EP-0406837-B1 | Cationic polysaccharides and reagents for their preparation | NAT STARCH CHEM INVEST (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5349089-A | N-/3-/haloethylethyl/aminopropyl/N,N,N-trimethylammonium salt | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| US-5227481-A | Cationic polysaccharides and reagents for their preparation | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0406837-A2 | Cationic polysaccharides and reagents for their preparation | National Starch and Chemical Investment Holding Corporation (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4661618-A | STIMULATION OF BRAIN CELLS AND MENTAL ACTIVITY; ANTIAGING AGENTS | BIOGAL GYOGYSZERGYAR (HU) | 1987-04-28 | — | — | US | disclosed |
| EP-0127000-B1 | 1,3-BIS(DIMETHYLAMINO)-2-PROPYL-4-CHLOROPHENOXYACETATE, ITS ADDITION SALTS, PROCESS FOR ITS PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THE AFORE-MENTIONED COMPOUNDS | BIOGAL GYOGYSZERGYAR (HU) | 1987-01-07 | — | — | EP | disclosed |
| EP-0127000-A1 | 1,3-Bis(dimethylamino)-2-propyl-4-chlorophenoxyacetate, its addition salts, process for its production and pharmaceutical preparations containing the afore-mentioned compounds | BIOGAL GYOGYSZERGYAR (HU) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143383-A1 | Pharmaceutical compounds | CHRNA10, OPRM1, SCN10A | HTR2A 308/4885HRH1 174/4885TDP1 4765/4885 |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | TOP1, TOP2A, TOP2B | HTR2A 1304/4885HRH1 1145/4885TDP1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.