Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | FCER2 | P06734 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986869 | 1.00 | MMP1 (0.48) | MMP1MMP9MMP14MMP2MMP3 | |
| SCHEMBL5886614 | 0.90 | MMP1 (0.56) | MMP1MMP9MMP2MMP3FCER2 | |
| SCHEMBL5886611 | 0.90 | MMP1 (0.56) | MMP1MMP9MMP2MMP3FCER2 | |
| SCHEMBL5886644 | 0.85 | MMP1 (0.63) | MMP1MMP9MMP14MMP2MMP3 | |
| SCHEMBL13986872 | 0.85 | MMP1 (0.63) | MMP1MMP9MMP14MMP2MMP3 | |
| SCHEMBL5886593 | 0.77 | MMP1 (0.44) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL13986864 | 0.77 | MMP1 (0.44) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL24915422 | 0.75 | MME (0.52) | MMP1MMP9MMP14MMP2MMP3 | |
| SCHEMBL16571327 | 0.75 | KMT2A (0.52) | MMP9MMP14MMP8CTSD | |
| SCHEMBL18064459 | 0.75 | KMT2A (0.52) | MMP9MMP14MMP8CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101864-B1 | Compositions comprising oxophosphonate-based metalloproteinase inhibitors | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-05 | — | — | US | claimed |
| EP-1223945-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-24 | — | — | EP | claimed |
| WO-2001026661-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-04-19 | — | — | WO | claimed |