Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 9/20 | 0.42 |
| ▸ | MMP8 | P22894 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986864 | 1.00 | MMP1 (0.44) | MMP1LAP3MMP2MMP8MMP9 | |
| SCHEMBL5886634 | 0.84 | FPR2 (0.39) | MMP1LAP3MMP2MMP8MMP9 | |
| SCHEMBL17920203 | 0.82 | MMP9 (0.43) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL13521930 | 0.82 | MMP9 (0.43) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL12628471 | 0.82 | MMP9 (0.43) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL5886609 | 0.77 | MMP1 (0.48) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL13986869 | 0.77 | MMP1 (0.48) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL13986872 | 0.75 | MMP1 (0.63) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL5886644 | 0.75 | MMP1 (0.63) | MMP1MMP2MMP8MMP9MMP3 | |
| SCHEMBL7364063 | 0.75 | LAP3 (0.70) | MMP1LAP3MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101864-B1 | Compositions comprising oxophosphonate-based metalloproteinase inhibitors | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-05 | — | — | US | claimed |