Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 6/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887369 | 0.87 | KDM4E (0.41) | NAMPTKDM4EKLKB1MEN1KMT2A | |
| SCHEMBL5887280 | 0.86 | CTNNB1 (0.40) | NAMPTKLKB1MEN1KMT2APPARG | |
| SCHEMBL5886824 | 0.86 | CTNNB1 (0.41) | NAMPTKLKB1KMT2APPARGHTR7 | |
| SCHEMBL5887290 | 0.85 | ALDH1A1 (0.44) | KDM4EEPHX2RAB9AALDH1A1 | |
| SCHEMBL5887324 | 0.85 | ALDH1A1 (0.37) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5887408 | 0.85 | PPARG (0.35) | NAMPTKDM4EKLKB1MEN1KMT2A | |
| SCHEMBL5886756 | 0.84 | PPARG (0.41) | NAMPTKDM4EMEN1KMT2APPARG | |
| SCHEMBL5887198 | 0.84 | MAPT (0.43) | NAMPTKLKB1PPARGHTR7CTNNB1 | |
| SCHEMBL5887590 | 0.84 | MIF (0.40) | NAMPTKDM4EKLKB1PPARGHTR7 | |
| SCHEMBL5887137 | 0.84 | CTNNB1 (0.41) | NAMPTKLKB1PPARGHTR7CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019002-B2 | Substituted on 8th position with benzoic acid, ester or amide groups; anticancer agents | PHARMACIA & UPJOHN, S.P.A. (IT) | 2006-03-28 | — | — | US | claimed |
| US-20040009993-A1 | Pyridopyrimidinones derivatives as telomerase inhibitors | PHARMACIA ITALIA S.P.A. | 2004-01-15 | — | — | US | claimed |
| US-7019002-B2 | Substituted on 8th position with benzoic acid, ester or amide groups; anticancer agents | PHARMACIA & UPJOHN, S.P.A. (IT) | 2006-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009993-A1 | Pyridopyrimidinones derivatives as telomerase inhibitors | TERT, TERF2, TERF2IP | NAMPT 527/4885KDM4E 840/4885KLKB1 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.