SCHEMBL5887430

SCHEMBL5887430

Cc1cc(C)c(Sc2ccccc2)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.44
POLB P06746 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40
AKR1B1 P15121 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
ACHE P22303 1/20 0.38
MMP1 P03956 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14393959 0.85 AR (0.41) ARCYP1A2CYP2A6ALDH1A1LMNA
SCHEMBL13386343 0.84 AR (0.49) ARTDP1CYP1A2ALDH1A1GAA
SCHEMBL13915410 0.83 AR (0.45) ARALDH1A1MEN1KMT2AACHE
SCHEMBL5887695 0.81 TSHR (0.43) ARPOLBTDP1CYP1A2CYP2A6
SCHEMBL25517553 0.78 CA12 (0.41) POLBTDP1AKR1B1PTGDR2ALDH1A1
SCHEMBL15986534 0.78 LMNA (0.40) POLBTDP1AKR1B1PTGDR2ALDH1A1
SCHEMBL16326824 0.78 AR (0.45) ARAKR1B1PTGDR2GAACYP2C9
SCHEMBL11192792 0.78 NR1H2 (0.52) ARPOLBTDP1ALDH1A1GAA
SCHEMBL9486952 0.77 POLB (0.40) POLBTDP1AKR1B1PTGDR2ALDH1A1
SCHEMBL9935610 0.77 RAPGEF4 (0.43) ARTDP1CYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115055927-B Preparation method of high-strength high-temperature-resistant numerical control drill bit 吉安富奇精密制造有限公司 2024-02-09 CN claimed
CN-115055927-A Preparation method of high-strength high-temperature-resistant numerical control drill bit 吉安富奇精密制造有限公司 2022-09-16 CN claimed
CN-117645540-A Preparation method of chlorophenoxycarboxylate 山东润博生物科技有限公司 2024-03-05 CN disclosed
CN-115055927-B Preparation method of high-strength high-temperature-resistant numerical control drill bit 吉安富奇精密制造有限公司 2024-02-09 CN disclosed
CN-115055927-A Preparation method of high-strength high-temperature-resistant numerical control drill bit 吉安富奇精密制造有限公司 2022-09-16 CN disclosed
EP-2784055-A1 Fluoroform synthesis and uses thereof in the preparation of trifluoromethylated compounds Institut National des Sciences Appliquées de Rouen (INSA) (FR) 2014-10-01 EP disclosed
US-7544461-B2 Near infrared ray activation type positive resin composition KANSAI PAINT CO., LTD. (JP) 2009-06-09 US disclosed
US-20090045552-A1 Positive resist composition for recording medium master, and method of producing recording medium master and method of producing stamper using the same IMAI GENJI 2009-02-19 US disclosed
US-7432034-B2 Negative resist composition FUJIFILM CORPORATION (JP) 2008-10-07 US disclosed
US-20080096130-A1 POSITIVE RESIST COMPOSITION FUJIFILM CORPORATION 2008-04-24 US disclosed
US-7361446-B2 Sensitivity, high resolution, good pattern profile, used for super-microlithography FUJIFILM CORPORATION (JP) 2008-04-22 US disclosed
US-7338740-B2 Positive resist composition FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070259279-A1 Near Infrared Ray Activation Type Positive Resin Composition KANSAI PAINT CO., LTD. (JP) 2007-11-08 US disclosed
US-7279265-B2 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7250246-B2 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
US-7179578-B2 Positive resist composition FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-7163776-B2 Positive-working resist composition FUJI PHOTO FILM CO., LTD. (JP) 2007-01-16 US disclosed
US-7112697-B1 Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2006-09-26 US disclosed