SCHEMBL9935610

SCHEMBL9935610

Cc1cc(C)c(Sc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 5/20 0.43
AR P10275 2/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14163150 0.87 RAPGEF4 (0.41) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL13386073 0.87 AR (0.35) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL9713549 0.81 SELL (0.48) RAPGEF4MEN1KMT2AALDH1A1KDM4E
Dimesityl Disulfide SCHEMBL896126 0.80 RAPGEF4 (0.43) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL11745730 0.79 ALDH1A1 (0.42) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL14252164 0.79 MEN1 (0.33) RAPGEF4ARMEN1KMT2A
SCHEMBL19500052 0.79 AR (0.34) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL13386343 0.79 AR (0.49) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL758797 0.78 RAPGEF4 (0.41) RAPGEF4ARMEN1KMT2AALDH1A1
SCHEMBL5887430 0.77 AR (0.44) ARMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466730-A Preparation method of phenoxy carboxylate herbicide 山东润博生物科技有限公司 2024-01-30 CN claimed
WO-2019179288-A2 PREPARATION METHOD FOR CHLOROPHENOXYCARBOXYLATE 山东润博生物科技有限公司 2019-09-26 WO claimed
CN-108947811-A Preparation method of phenoxy carboxylate herbicide 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947805-A A kind of preparation method of phenoxy carboxylic acid choline salt 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947804-A A kind of preparation method of chlorobenzene oxycarboxylic acid substance 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947838-A A kind of preparation method of 2,4 dichlorophenoxyacetic acid and its salt 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947837-A A kind of preparation method of 2,4 dichlorophenoxyacetic acid ester 山东润博生物科技有限公司 2018-12-07 CN claimed
CN-108947799-A A kind of preparation method of chlorobenzene oxycarboxylic acid 山东润博生物科技有限公司 2018-12-07 CN claimed
US-20260001875-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE UNIV DUNDEE (GB) 2026-01-01 US disclosed
EP-4522603-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE University Of Dundee (GB) 2025-03-19 EP disclosed
CN-117736082-A Preparation method of phenoxy carboxylic acid herbicide 山东润博生物科技有限公司 2024-03-22 CN disclosed
CN-117466730-A Preparation method of phenoxy carboxylate herbicide 山东润博生物科技有限公司 2024-01-30 CN disclosed
EP-4276097-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE University Of Dundee (GB) 2023-11-15 EP disclosed
WO-2019179267-A1 PREPARATION METHOD OF PHENOXYCARBOXYLIC ACID HERBICIDES 山东润博生物科技有限公司 2019-09-26 WO disclosed
US-20080139768-A1 Copolymer Having Cyclic Ether Structure in Main Chain, Optical Member Comprising the Copolymer, and Method of Producing the Same FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080139768-A1 Copolymer Having Cyclic Ether Structure in Main Chain, Optical Member Comprising the Copolymer, and Method of Producing the Same FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080124508-A1 Method For Producing Refractive Index Profile Plastic Optical Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
US-20080124508-A1 Method For Producing Refractive Index Profile Plastic Optical Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001875-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE LRRK2, XIAP, PARK7 RAPGEF4 1338/4885AR 2729/4885MEN1 3794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.