Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887473 | 1.00 | TACR1 (0.69) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL30621980 | 0.92 | TACR1 (0.80) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL8710942 | 0.89 | TACR1 (0.72) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL8710945 | 0.89 | TACR1 (0.72) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL5887384 | 0.88 | TACR1 (0.60) | TACR1CTSSCTSKALDH1A1ALOX15 | |
| SCHEMBL5887381 | 0.88 | TACR1 (0.60) | TACR1CTSSCTSKALDH1A1ALOX15 | |
| SCHEMBL2853641 | 0.87 | TACR1 (0.69) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL2853645 | 0.87 | TACR1 (0.69) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL5887863 | 0.87 | TACR1 (0.69) | TACR1POLBACEMBTPS1CTSS | |
| SCHEMBL5887859 | 0.87 | TACR1 (0.69) | TACR1POLBACEMBTPS1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091373-B2 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | TACR1 2442/4885POLB 3282/4885ACE 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.