Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886952 | 0.88 | HPGD (0.58) | HPGDSMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL5886906 | 0.87 | MMP13 (0.40) | HPGDSMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL5887047 | 0.85 | HPGD (0.54) | HPGDSMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL5886972 | 0.85 | MEN1 (0.37) | HPGDSMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL5886978 | 0.85 | HPGD (0.54) | HPGDSMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL5886746 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2RAB9ALMNAPOLBMAPT | |
| SCHEMBL5887294 | 0.83 | MAPK8 (0.40) | HPGDSMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL5887335 | 0.83 | L3MBTL1 (0.39) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL5886844 | 0.83 | MAPT (0.44) | HPGDSMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL5887213 | 0.82 | HPGD (0.45) | HPGDSMN1; SMN2LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019002-B2 | Substituted on 8th position with benzoic acid, ester or amide groups; anticancer agents | PHARMACIA & UPJOHN, S.P.A. (IT) | 2006-03-28 | — | — | US | claimed |