Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888342 | 0.85 | DAO (0.40) | TSHRMAPTALDH1A1KDM4E | |
| SCHEMBL1529648 | 0.82 | USP2 (0.51) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL5888101 | 0.76 | USP10 (0.49) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL6967133 | 0.75 | ALOX5 (0.33) | MAPTHSD17B10ALDH1A1KDM4EPPARG | |
| SCHEMBL10088560 | 0.75 | OPRD1 (0.47) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL17201680 | 0.74 | PTPN2 (0.43) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL18420119 | 0.73 | HPGD (0.46) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL19002552 | 0.72 | ALDH1A1 (0.43) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL16901555 | 0.71 | HPGD (0.54) | MAPK1HPGDNPSR1L3MBTL1TSHR | |
| SCHEMBL16639425 | 0.71 | HPGD (0.42) | MAPK1HPGDNPSR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7052742-B1 | Five membered-ring compounds and utilization thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2006-05-30 | — | — | US | disclosed |