SCHEMBL5888032

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2617274	1.00	ATM (0.58)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL2617272	0.91	REN (0.58)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL6499797	0.91	REN (0.58)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL272406	0.90	ATM (0.59)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL5410539	0.90	ATM (0.59)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL272806	0.90	ATM (0.59)	ATMBCL2PTPN1ITGB3ITGA2B
	SCHEMBL489489	0.89	ATM (0.70)	ATMSYKAPPCTSSCTSL
	SCHEMBL489490	0.89	ATM (0.70)	ATMSYKAPPCTSSCTSL
	SCHEMBL1519945	0.89	ATM (0.70)	ATMSYKAPPCTSSCTSL
	SCHEMBL31758125	0.89	ATM (0.53)	ATMBCL2PTPN1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.