Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888153 | 1.00 | PRCP (0.54) | PRCPSMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL5218642 | 0.94 | ALDH1A1 (0.54) | PRCPSMN1; SMN2LMNARAB9ACTSL | |
| SCHEMBL5888633 | 0.94 | ALDH1A1 (0.54) | PRCPSMN1; SMN2LMNARAB9ACTSL | |
| SCHEMBL30795674 | 0.94 | ALDH1A1 (0.54) | PRCPSMN1; SMN2LMNARAB9ACTSL | |
| SCHEMBL5888420 | 0.93 | ALDH1A1 (0.50) | PRCPSMN1; SMN2LMNARAB9ACTSL | |
| SCHEMBL5888528 | 0.89 | KMT2A (0.56) | PRCPCYP3A4CYP2C9KMT2AALDH1A1 | |
| SCHEMBL5888533 | 0.89 | KMT2A (0.56) | PRCPCYP3A4CYP2C9KMT2AALDH1A1 | |
| SCHEMBL5888640 | 0.84 | LMNA (0.47) | PRCPSMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL5888892 | 0.84 | PRCP (0.52) | PRCPSMN1; SMN2LMNARAB9AKMT2A | |
| SCHEMBL5888887 | 0.84 | PRCP (0.52) | PRCPSMN1; SMN2LMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135472-B2 | 3-Heterocyclic benzylamide derivatives as potassium channel openers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-14 | — | — | US | disclosed |