Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888887 | 1.00 | PRCP (0.52) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888640 | 0.88 | LMNA (0.47) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888642 | 0.88 | LMNA (0.47) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888153 | 0.84 | PRCP (0.54) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888147 | 0.84 | PRCP (0.54) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30795674 | 0.78 | ALDH1A1 (0.54) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5888633 | 0.78 | ALDH1A1 (0.54) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5218642 | 0.78 | ALDH1A1 (0.54) | PRCPLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6626296 | 0.77 | TDP1 (0.59) | LMNARAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6626299 | 0.77 | TDP1 (0.59) | LMNARAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135472-B2 | 3-Heterocyclic benzylamide derivatives as potassium channel openers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-14 | — | — | US | disclosed |