Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772009 | 0.88 | DRD2 (0.53) | DRD2MCHR1 | |
| SCHEMBL5923750 | 0.87 | DRD2 (0.56) | DRD2MCHR1 | |
| SCHEMBL5521956 | 0.85 | DRD2 (0.53) | DRD2MCHR1 | |
| SCHEMBL5508600 | 0.84 | DRD2 (0.56) | DRD2MCHR1 | |
| SCHEMBL4765157 | 0.84 | DRD2 (0.54) | DRD2 | |
| SCHEMBL4768518 | 0.79 | DRD2 (0.47) | DRD2 | |
| SCHEMBL4794082 | 0.79 | ADRA1D (0.62) | — | |
| SCHEMBL5923679 | 0.77 | DRD2 (0.44) | DRD2 | |
| SCHEMBL5923658 | 0.76 | DRD2 (0.48) | DRD2MCHR1 | |
| SCHEMBL4791777 | 0.76 | OPRM1 (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105544-B2 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20060041139-A9 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | H. LUNDBECK A/S (DK) | 2006-02-23 | — | — | US | disclosed |
| US-20040186103-A1 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-09-23 | — | — | US | disclosed |
| US-20040073036-A1 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073036-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | DRD2 74/4885MCHR1 1/4885 |
| US-20060041139-A9 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | MCHR1, MCHR2, MC1R | DRD2 74/4885MCHR1 1/4885 |
| US-20040186103-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | DRD2 74/4885MCHR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.