⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339039 | 0.79 | — | — | |
| SCHEMBL10039814 | 0.74 | NPSR1 (0.41) | — | |
| SCHEMBL2972762 | 0.74 | NPSR1 (0.41) | — | |
| SCHEMBL359078 | 0.74 | NPSR1 (0.41) | — | |
| SCHEMBL9056776 | 0.73 | ALDH1A1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL15967648 | 0.72 | NPSR1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL1357772 | 0.72 | NPSR1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL15967647 | 0.72 | NPSR1 (0.39) | — | |
| SCHEMBL10957286 | 0.71 | OPRM1 (0.40) | — | |
| SCHEMBL28426667 | 0.71 | OPRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125702-B2 | Process for the preparation of angiotensis converting enzyme (ACE) inhibitors and its use | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-24 | — | — | US | disclosed |
| US-20060073543-A1 | Process for the preparation of angiotensis converting enzyme (ACE) inhibitors and its use | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-06 | — | — | US | disclosed |
| WO-2004085664-A2 | PROCESS FOR THE PREPARATION OF ANGIOTENSIN CONVERTING ENZYME (ACE) INHIBITORS AND ITS USE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-07 | — | — | WO | disclosed |
| US-20040191857-A1 | Process for the preparation of angiotensis converting enzyme (ACE) inhibitors and its use | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-09-30 | — | — | US | disclosed |
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4046889-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANGIOTENSIN CONVERSION | E. R. SQUIBB & SONS, INC. (US) | 1977-09-06 | — | — | US | disclosed |