SCHEMBL5889194

SCHEMBL5889194

Brc1ccc(-c2ccc(-c3ccc(-c4ccc(-c5ccc(Br)s5)s4)s3)s2)s1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.48
MAPT P10636 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX12 P18054 2/20 0.46
ALOX15 P16050 1/20 0.46
KDM4E B2RXH2 4/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RXFP1 Q9HBX9 3/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
PPARG P37231 2/20 0.43
NCOA2 Q15596 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
NCOA1 Q15788 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5889177 1.00 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL5453288 1.00 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL498474 1.00 SNCA (0.48) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL197157 0.97 SNCA (0.50) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL16140274 0.91 SNCA (0.43) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL12964479 0.84 SNCA (0.39) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL8508163 0.84 MAPT (0.42) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL12964481 0.83 SNCA (0.38) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL2778388 0.81 SNCA (0.61) SNCAMAPTMEN1KMT2AHSD17B10
SCHEMBL4090912 0.81 MAPT (0.44) SNCAMAPTMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6986952-B2 Chemical compound capable of emitting visible light, and luminescent material, electro-luminescent device, and display apparatus that contain the chemical compound MITSUMI ELECTRIC CO., LTD. (JP) 2006-01-17 US disclosed
US-20040166363-A1 Chemical compound capable of emitting visible light, and luminescent material, electro-luminescent device, and display apparatus that contain the chemical compound MITSUMI ELECTRIC CO., LTD. 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166363-A1 Chemical compound capable of emitting visible light, and luminescent material, electro-luminescent device, and display apparatus that contain the chemical compound EML4, DDT, EED SNCA 1089/4885MAPT 2130/4885MEN1 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.