SCHEMBL5889229

SCHEMBL5889229

c1ccc2c(c1)C(=NNc1cccc3ccccc13)c1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
MAPT P10636 5/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 4/20 0.44
HSD17B10 Q99714 4/20 0.44
ATM Q13315 2/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 2/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
CDC25B P30305 1/20 0.44
GAA P10253 4/20 0.43
SIGMAR1 Q99720 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922339 0.77 KDM4E (0.42) ALDH1A1MAPTTSHRHSD17B10ATM
SCHEMBL11968417 0.77 KDM4E (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL30702588 0.77 KDM4E (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11876684 0.77 KDM4E (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL3842734 0.72 KDM4E (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL9055550 0.72 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL49213 0.68 HSD17B10 (0.74) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL7915675 0.68 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL19837583 0.68 ALDH1A1 (0.46) ALDH1A1MAPTSMN1; SMN2TSHRHSD17B10
SCHEMBL13624676 0.68 KEAP1 (0.46) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7063928-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO LTD. (KR) 2006-06-20 US claimed
US-6905804-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-06-14 US claimed
US-20050123849-A1 An apparatus having an organophotoreceptor in the form of a flexible belt threaded around support rollers and having a charge transfer compound comprising a fluorenone hydrazone including other functional groups and phenyl and heteraryl rings;used with liquid toner; durability SAMSUNG ELECTRONICS CO., LTD. 2005-06-09 US claimed
US-20030198880-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-10-23 US claimed
EP-1335250-A1 Electrophotographic organophotoreceptors with novel charge transport materials Samsung Electronics Co., Ltd. (KR) 2003-08-13 EP claimed
CN-1287227-C Electric photographic organic photoreceptor with new charge transfer matter SAMSUNG ELECTRONICS CO LTD (KR) 2006-11-29 CN disclosed
US-7063928-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO LTD. (KR) 2006-06-20 US disclosed
US-7063928-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO LTD. (KR) 2006-06-20 US disclosed
US-6905804-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-06-14 US disclosed
US-6905804-B2 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-06-14 US disclosed
US-20050123849-A1 An apparatus having an organophotoreceptor in the form of a flexible belt threaded around support rollers and having a charge transfer compound comprising a fluorenone hydrazone including other functional groups and phenyl and heteraryl rings;used with liquid toner; durability SAMSUNG ELECTRONICS CO., LTD. 2005-06-09 US disclosed
US-20050123849-A1 An apparatus having an organophotoreceptor in the form of a flexible belt threaded around support rollers and having a charge transfer compound comprising a fluorenone hydrazone including other functional groups and phenyl and heteraryl rings;used with liquid toner; durability SAMSUNG ELECTRONICS CO., LTD. 2005-06-09 US disclosed
US-20030198880-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-10-23 US disclosed
US-20030198880-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-10-23 US disclosed
CN-1445615-A Electric photographic organic photoreceptor with new charge transfer matter SAMSUNG ELECTRONICS CO LTD (KR) 2003-10-01 CN disclosed
JP-2003270828-A ORGANOPHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD AND CHARGE TRANSPORT MATERIAL SAMSUNG ELECTRONICS CO LTD 2003-09-25 JP disclosed
EP-1335250-A1 Electrophotographic organophotoreceptors with novel charge transport materials Samsung Electronics Co., Ltd. (KR) 2003-08-13 EP disclosed
EP-1335250-A1 Electrophotographic organophotoreceptors with novel charge transport materials Samsung Electronics Co., Ltd. (KR) 2003-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050123849-A1 An apparatus having an organophotoreceptor in the form of a flexible belt threaded around support rollers and having a charge transfer compound comprising a fluorenone hydrazone including other functional groups and phenyl and heteraryl rings;used with liquid toner; durability HTR3D, SLCO1B3, FLNB ALDH1A1 2486/4885MAPT 734/4885MEN1 789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.