SCHEMBL19837583

SCHEMBL19837583

c1ccc2c(c1)-c1ccccc1C2Nc1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
HPGD P15428 6/20 0.46
HSD17B10 Q99714 6/20 0.46
TSHR P16473 4/20 0.46
CYP3A4 P08684 2/20 0.46
TP53 P04637 1/20 0.46
ALOX15 P16050 1/20 0.46
CDC25B P30305 1/20 0.46
ATM Q13315 1/20 0.46
KDM4E B2RXH2 6/20 0.44
MAPT P10636 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 3/20 0.43
CASP3 P42574 2/20 0.43
SENP8 Q96LD8 2/20 0.43
SENP7 Q9BQF6 2/20 0.43
SENP6 Q9GZR1 2/20 0.43
APAF1 O14727 1/20 0.43
NSD2 O96028 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19837482 0.91 HPRT1 (0.48) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL28525832 0.84 HPGD (0.37) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL13218576 0.83 DNMT1 (0.42) ALDH1A1HPGDHSD17B10TSHRATM
SCHEMBL29040922 0.83 CYP2A6 (0.42) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL16481156 0.75 KDM1A (0.48) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL6675754 0.75 KDM1A (0.53) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL19269579 0.74 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL19733161 0.74 PARP14 (0.50) TP53MAPTHTT
SCHEMBL9008311 0.72 ROCK2 (0.58) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL29447185 0.72 ROCK2 (0.58) ALDH1A1HPGDHSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351523-B1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2020-11-04 EP claimed
CN-107428639-B Double-spiro compound and organic light-emitting element comprising same 株式会社LG化学 2020-10-30 CN claimed
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US claimed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US claimed
EP-3321246-B1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP claimed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US claimed
EP-3351523-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
EP-3351531-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US claimed
EP-3321246-A2 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-05-16 EP claimed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US claimed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US claimed
US-20260140440-A1 METHOD FOR FORMING PHOTORESIST THIN FILM REACTIVE TO EXTREME ULTRAVIOLET RAYS, AND PHOTORESIST THIN FILM FORMED THEREBY DONGJIN SEMICHEM CO LTD (KR) 2026-05-21 US disclosed
US-12606563-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2026-04-21 US disclosed
US-12610736-B2 Organic light emitting device LG CHEM, LTD. (KR) 2026-04-21 US disclosed
US-20260107683-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2026-04-16 US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
EP-3321246-A2 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-05-16 EP disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606563-B2 Organic light-emitting device CYBA, CRY2, CRY1 ALDH1A1 1439/4885HPGD 3371/4885HSD17B10 2410/4885
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG ALDH1A1 33/4885HPGD 2229/4885HSD17B10 1154/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 ALDH1A1 87/4885HPGD 3642/4885HSD17B10 2296/4885
US-12610736-B2 Organic light emitting device NR2E3, NR0B2, NR2E1 ALDH1A1 466/4885HPGD 2587/4885HSD17B10 1665/4885
US-20260107683-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CHRM1 ALDH1A1 199/4885HPGD 3981/4885HSD17B10 2220/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 ALDH1A1 87/4885HPGD 3642/4885HSD17B10 2296/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 ALDH1A1 486/4885HPGD 1749/4885HSD17B10 2413/4885
US-20260140440-A1 METHOD FOR FORMING PHOTORESIST THIN FILM REACTIVE TO EXTREME ULTRAVIOLET RAYS, AND PHOTORESIST THIN FILM FORMED THEREBY PPOX, HAO2, PF4 ALDH1A1 1808/4885HPGD 153/4885HSD17B10 1241/4885
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, PER2 ALDH1A1 486/4885HPGD 1749/4885HSD17B10 2413/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 ALDH1A1 73/4885HPGD 2499/4885HSD17B10 1296/4885
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME NR2E3, CRY1, CRY2 ALDH1A1 73/4885HPGD 2499/4885HSD17B10 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.