Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889916 | 0.95 | HDAC2 (0.48) | HDAC2KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL5889594 | 0.95 | TERT (0.47) | HDAC2KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL5889980 | 0.94 | TERT (0.51) | HDAC2KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL5889665 | 0.90 | ITGB3 (0.51) | HDAC2KDM4EITGB3ITGA2BPLD2 | |
| SCHEMBL5889931 | 0.89 | TERT (0.53) | HDAC2KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL5890009 | 0.88 | ITGB3 (0.44) | HDAC2ITGB3ITGA2BNHERF1PLD2 | |
| SCHEMBL5889938 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL5889883 | 0.88 | ITGB3 (0.47) | HDAC2ITGB3ITGA2BNHERF1PLD2 | |
| SCHEMBL5889537 | 0.87 | KDM4E (0.51) | HDAC2KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL5889588 | 0.86 | HDAC2 (0.48) | HDAC2KDM4EITGB3ITGA2BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064218-B2 | Aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2006-06-20 | — | — | US | disclosed |
| US-6906103-B2 | Compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6849713-B2 | Compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | GLAXOSMITHKLINE LLC | 2003-11-13 | — | — | US | disclosed |
| US-20030119749-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | SMITHKLINE BEECHAM CORPORATION | 2003-06-26 | — | — | US | disclosed |
| US-20020037856-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119749-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | CYP51A1, MCL1, ERG28 | HDAC2 1132/4885KDM4E 3560/4885HSD17B10 2227/4885 |
| US-20020037856-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | CYP51A1, MCL1, ERG28 | HDAC2 1132/4885KDM4E 3560/4885HSD17B10 2227/4885 |
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | TYR, CYP51A1, ODC1 | HDAC2 2108/4885KDM4E 1515/4885HSD17B10 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.