Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889634 | 1.00 | LMNA (0.50) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7782645 | 0.86 | LMNA (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7779981 | 0.81 | LMNA (0.46) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7042726 | 0.81 | LMNA (0.54) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7775513 | 0.79 | LMNA (0.55) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL16537552 | 0.77 | LMNA (0.54) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL1774828 | 0.77 | LMNA (0.46) | LMNAALDH1A1TRPA1TAAR1CCR5 | |
| SCHEMBL502912 | 0.76 | TRPA1 (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL3619718 | 0.76 | TRPA1 (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL3619720 | 0.76 | TRPA1 (0.47) | LMNAADRA2AADRA2CHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115296-B2 | N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20040071851-A1 | Novel N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO. INC (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6010733-A | ARTIFICIAL SWEETENER | AJINOMOTO CO., INC. (JP) | 2000-01-04 | — | — | US | disclosed |