Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335229 | 0.87 | TRPA1 (0.63) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL7691241 | 0.83 | TRPA1 (0.59) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL31706544 | 0.82 | TRPA1 (0.57) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL5889634 | 0.79 | LMNA (0.50) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL5889632 | 0.79 | LMNA (0.50) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL4433686 | 0.79 | TAAR1 (0.60) | LMNAADRA2AADRA2CHIF1ATRPA1 | |
| SCHEMBL4582172 | 0.79 | TRPA1 (0.63) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL2418955 | 0.79 | TRPA1 (0.63) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL6014452 | 0.79 | TAAR1 (0.60) | LMNAADRA2AADRA2CHIF1ATRPA1 | |
| SCHEMBL27360069 | 0.79 | TAAR1 (0.60) | LMNAADRA2AADRA2CHIF1ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784050-B1 | Novel aspartylamide derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0784050-A1 | Novel aspartylamide derivatives and sweeteners | Ajinomoto Co., Inc. (JP) | 1997-07-16 | — | — | EP | disclosed |