Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL9293254 | 1.00 | — | — | |
| Lithium Ion SCHEMBL589 | 0.96 | TSHR (0.31) | — | |
| Lithium Ion SCHEMBL14812375 | 0.93 | — | — | |
| Lithium Ion SCHEMBL2059893 | 0.93 | — | — | |
| Lithium Ion SCHEMBL11332262 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL3898653 | 0.89 | TSHR (0.31) | — | |
| Lithium Ion SCHEMBL11332267 | 0.89 | TSHR (0.31) | — | |
| Lithium Ion SCHEMBL808460 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL107947 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL1939142 | 0.85 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |