SCHEMBL5890628

SCHEMBL5890628

CC(C)CC1=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc2C1[Hf](Cl)(Cl)(C1C(CC(C)C)=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818623 0.86 ALOX15 (0.30)
SCHEMBL5890464 0.86 ALOX15 (0.31)
SCHEMBL5890191 0.85
SCHEMBL5890609 0.85 GABRA1 (0.31)
SCHEMBL5890899 0.84
SCHEMBL1120672 0.84 ALOX15 (0.31)
SCHEMBL5890821 0.84 CNR1 (0.33)
SCHEMBL5890962 0.83
SCHEMBL5890213 0.83 NPC1 (0.35) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL3697568 0.83 CNR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122498-B2 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-10-17 US disclosed