Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817965 | 0.93 | NPC1 (0.33) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5890665 | 0.89 | NPC1 (0.33) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5890334 | 0.84 | — | — | |
| SCHEMBL5889869 | 0.84 | — | — | |
| SCHEMBL818446 | 0.84 | — | — | |
| SCHEMBL5890628 | 0.83 | NPC1 (0.31) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL818878 | 0.83 | KDM4E (0.34) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7933119 | 0.82 | ALOX5 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL7935517 | 0.82 | NPC1 (0.31) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL5889755 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122498-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-10-17 | — | — | US | disclosed |