Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375626 | 0.81 | HDAC3 (0.56) | FAAHACHEBCHE | |
| SCHEMBL24001121 | 0.81 | CNR1 (0.45) | — | |
| SCHEMBL4369989 | 0.79 | CA12 (0.45) | CA1CA2ACHEBCHE | |
| SCHEMBL590652 | 0.79 | RAB9A (0.52) | MAPTCA2BCHE | |
| SCHEMBL4374257 | 0.79 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL4368215 | 0.78 | ALOX15 (0.53) | SIGMAR1MAPT | |
| SCHEMBL12916046 | 0.78 | SIGMAR1 (0.64) | FAAHSIGMAR1MAPTACHEBCHE | |
| SCHEMBL5859633 | 0.77 | NAMPT (0.53) | — | |
| SCHEMBL23455649 | 0.76 | SMN1; SMN2 (0.54) | MAPTBCHE | |
| SCHEMBL17468810 | 0.75 | SIGMAR1 (0.61) | FAAHSIGMAR1MAPTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114877-B2 | Antiinflammatory agnets; chronic obstructive pulmonary diseases | NOVARTIS AG (CH) | 2012-02-14 | — | — | US | disclosed |